Ever wonder why some people seem to feel less pain than others? A study conducted at Wake Forest School of Medicine may have found one of the answers – mindfulness.
“Mindfulness is related to being aware of the present moment without too much emotional reaction or judgment,” said the study’s lead author, Fadel Zeidan, Ph.D., assistant professor of neurobiology and anatomy at the medical school, part of Wake Forest Baptist Medical Center.
“We now know that some people are more mindful than others, and those people seemingly feel less pain.”
This study was published in September 2018 in the journal PAIN. The researchers analyzed data obtained from a study published in 2015 that compared mindfulness meditation to placebo analgesia. In this follow-up study, Zeidan sought to determine if dispositional mindfulness, an individual’s innate or natural level of mindfulness, was associated with lower pain sensitivity, and to identify what brain mechanisms were involved.
In the study, 76 healthy volunteers who had never meditated first completed the Freiburg Mindfulness Inventory, a reliable clinical measurement of mindfulness, to determine their baseline levels. Then, while undergoing functional magnetic resonance imaging, they were administered painful heat stimulation (120°F).
Whole brain analyses revealed that higher dispositional mindfulness during painful heat was associated with greater deactivation of a brain region called the posterior cingulate cortex, a central neural node of the default mode network. Further, in those that reported higher pain, there was greater activation of this critically important brain region.
The default mode network extends from the posterior cingulate cortex to the medial prefrontal cortex of the brain. These two brain regions continuously feed information back and forth. This network is associated with processing feelings of self and mind wandering, Zeidan said.
“As soon as you start performing a task, the connection between these two brain regions in the default mode network disengages and the brain allocates information and processes to other neural areas,” he said.
“Default mode deactivates whenever you are performing any kind of task, such as reading or writing. Default mode network is reactivated whenever the individual stops performing a task and reverts to self-related thoughts, feelings and emotions. The results from our study showed that mindful individuals are seemingly less caught up in the experience of pain, which was associated with lower pain reports.”
The study provided novel neurobiological information that showed people with higher mindfulness ratings had less activation in the central nodes (posterior cingulate cortex) of the default network and experienced less pain.
Those with lower mindfulness ratings had greater activation of this part of the brain and also felt more pain, Zeidan said.”Now we have some new ammunition to target this brain region in the development of effective pain therapies.”
“Importantly this work shows that we should consider one’s level of mindfulness when calculating why and how one feels less or more pain,” Zeidan added.
“Based on our earlier research, we know we can increase mindfulness through relatively short periods of mindfulness meditation training, so this may prove to be an effective way to provide pain relief for the millions of people suffering from chronic pain.”
The practice of Mindfulness is also getting more popular in Singapore with Brahm Centre reporting that the take-up rate for its mindfulness course has increased exponentially since they started in 2012 and have reached out to a wide audience of over 32,500 so far.
Brahm Centre which is a leading organisation which promotes mental health in Singapore, has also partnered with Duke-NUS in a local study involving some 96 participants, which demonstrated that a four-week mindfulness practice can reduce anxiety and ruminative thoughts before sleep, and that this reduction is associated with better sleep quality.
The study is being published in the journal, Mindfulness. These findings can help to adapt and refine the practice of mindfulness in the Singapore context for better outcomes in primary prevention of mental health conditions.